Medical Research

brain injury

cancer

endocrinology

fibromyalgia and crps

gastroenterology

inflammation

musculoskeletal

neurologic

peripheral neuropathy

post radiation

infection

stem cells

surgical

urology

wounds

 

 

 

Latest medical research data


BRAIN INJURY

Microglial activation induced by traumatic brain injury is suppressed by postinjury treatment with hyperbaric oxygen therapy

Long Course Hyperbaric Oxygen Stimulates Neurogenesis and Attenuates Inflammation after Ischemic Stroke

Hyperbaric Oxygen Induces Late Neuroplasticity in Post Stroke Patients – Randomized, Prospective Trial

Influence of hyperbaric oxygen treatment on neural plasticity in experimental rats.

Hyperbaric oxygen preconditioning induces tolerance against brain ischemia-reperfusion injury by upregulation of antioxidant enzymes in rats

Effect of hyperbaric oxygenation on brain hemodynamics, hemoglobin oxygenation and mitochondrial NADH

Therapeutic window of hyperbaric oxygen therapy for hypoxic-ischemic brain damage in newborn rats

Pilot case study of the therapeutic potential of hyperbaric oxygen therapy on chronic brain injury

Hyperbaric oxygen induces endogenous neural stem cells to proliferate and differentiate in hypoxic-ischemic brain damage in neonatal rats

Therapeutic effects of hyperbaric oxygen in a rat model of endothelin-1-induced focal cerebral ischemia

Hyperbaric oxygen treatment attenuated the decrease in regional glucose metabolism of rats subjected to focal cerebral ischemia: A high resolution positron emission tomography study

Effect of hyperbaric oxygen on patients with traumatic brain injury

Up-regulated HIF-1alpha is involved in the hypoxic tolerance induced by hyperbaric oxygen preconditioning

Hyperbaric oxygen therapy improves spatial learning and memory in a rat model of chronic traumatic brain injury

Changes of Wnt-3 protein during the proliferation of endogenous neural stem cells in neonatal rats with hypoxic-ischemic brain damage after hyperbaric oxygen therapy

Effect of hyperbaric oxygenation on neural stem cells and myelin in neonatal rats with hypoxic-ischemic brain damage

Long-term effects of early hyperbaric oxygen therapy on neonatal rats with hypoxic-ischemic brain damage

Effect of hyperbaric oxygenation on the differentiation of implanted human neural stem cells into neurons in vivo

Hyperbaric oxygen preconditioning induces tolerance against brain ischemia-reperfusion injury by up regulation of antioxidant enzymes in rats

Hyperbaric oxygen induces rapid protection against focal cerebral ischemia

Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease

Mechanisms of hyperbaric oxygen and neuroprotection in stroke

Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease

 

CANCER

The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer

Hyperbaric Oxygen Therapy for Hemorrhagic Radiation Cystitis

Comparison of the effects of 40% oxygen and two atmospheric absolute air pressure conditions on stress-induced premature senescence of normal human diploid fibroblasts.

Hyperbaric oxygen inhibits benign and malignant human mammary epithelial cell proliferation.

Apoptosis of T-leukemia and B-myeloma cancer cells induced by hyperbaric oxygen increased phosphorylation of p38 MAPK.

Hyperoxia retards growth and induces apoptosis, changes in vascular density and gene expression in transplanted gliomas in nude rats.

Hypoxic tumor cell radiosensitization: role of the iNOS/NO pathway.

Systemic chemotherapy using paclitaxel and carboplatin plus regional hyperthermia and hyperbaric oxygen treatment for non-small cell lung cancer with multiple pulmonary metastases: preliminary results.

The effect of hyperbaric oxygen on human oral cancer cells.

Hyperbaric oxygen does not accelerate latent in vivo prostate cancer: implications for the treatment of radiation-induced haemorrhagic cystitis.

The effect of hyperbaric oxygen therapy on tumour growth in a mouse model of colorectal cancer liver metastases.

A pilot study with long term follow up of hyperbaric oxygen pretreatment in patients with locally advanced breast cancer undergoing neo-adjuvant chemotherapy.

Apoptosis of T-leukemia and B-myeloma cancer cells induced by hyperbaric oxygen increased phosphorylation of p38 MAPK.

Evaluation of the effect of SMA-pirarubicin micelles on colorectal cancer liver metastases and of hyperbaric oxygen in CBA mice

Oxygenation measurements in head and neck cancers during hyperbaric oxygenation

Effects of hyperbaric oxygen exposure on experimental head and neck tumor growth, oxygenation, and vasculature

The effect of hyperbaric oxygen treatment on squamous cell cancer growth and tumor hypoxia.

Effects of hyperbaric oxygen therapy on tumor growth in murine model of PC-3 prostate cancer cell line

 

ENDOCRINOLOGY


Prevention of Autoimmune Diabetes and Induction of ?-Cell Proliferation in NOD Mice by Hyperbaric Oxygen Therapy

Hyperbaric oxygen therapy improves peripheral insulin sensitivity in humans

Potential benefits of hyperbaric oxygen therapy on atherosclerosis and glycaemic control in patients with diabetic foot

 

FIBROMYALGIA AND CRPS


The efficacy of hyperbaric oxygen therapy in the management of chronic fatigue syndrome.

Effectiveness of hyperbaric oxygen therapy in the treatment of complex regional pain syndrome

A new treatment modality for fibromyalgia syndrome: hyperbaric oxygen therapy

A novel treatment modality for myofascial pain syndrome: hyperbaric oxygen therapy

 

GASTROENTEROLOGY

Therapeutic effect of hyperbaric oxygen on inclusion body myositis. *This study was co-authored by Dr. Pete Stephens of Hyperbaric Therapy of the Lowcountry and can be fully accessed here: UHM 39-6-1


Hyperbaric oxygen treatment for inflammatory bowel disease: a systematic review and analysis

The effect of iNOS inhibitors and hyperbaric oxygen treatment in a rat model of experimental colitis

Hyperbaric oxygen therapy is as effective as dexamethasone in the treatment of TNBS-E-induced experimental colitis

Impact of hyperbaric oxygen therapy on the clinical course of acute pancreatitis and systemic inflammation response syndrome

Hyperbaric Oxygen Reduces Inflammatory Response in Acute Pancreatitis by Inhibiting NF-kappaB Activation

Hyperbaric oxygen therapy reduces the severity of necrotizing enterocolitis in a neonatal rat model.

Can hyperbaric oxygenation decrease doxorubicin hepatotoxicity and improve regeneration in the injured liver?

Down-Regulation of Hypoxia-Inducible Factor-1alpha by Hyperbaric Oxygen Attenuates the Severity of Acute Pancreatitis in Rats.

The effect of hyperbaric oxygen treatment on postoperative morbidity of left lobe donor in living donor adult liver transplantation

Effects of hyperbaric oxygen and Pgg-glucan on ischemic colon anastomosis

Hyperbaric oxygen therapy as a prophylactic and treatment against ileus and recurrent intestinal obstruction soon after surgery to relieve adhesive intestinal obstruction

The effects of hyperbaric oxygen therapy on colonic anastomosis in rats with peritonitis

Preoperative and postoperative administration of hyperbaric oxygen improves biochemical and mechanical parameters on ischemic and normal colonic anastomoses

INFECTION

Role of hyperbaric oxygen therapy in the treatment of bacterial spinal osteomyelitis

Hyperbaric hyperoxia suppresses growth of Staphylococcus aureus , including methicillin-resistant strains

Hyperbaric hyperoxia suppresses growth of Staphylococcus aureus, including methicillin-resistant strains

The effect of the hyperbaric oxygen and closed irrigation-suction therapy on the methicillin-resistant Staphylococcus aureus (MRSA) Osteomyelitis

 

INFLAMMATION

Hyperbaric oxygen treatment is comparable to acetylsalicylic acid treatment in an animal model of arthritis

Hyperbaric oxygen treatment decreases inflammation and mechanical hypersensitivity in an animal model of inflammatory pain

Hyperbaric oxygen treatment attenuates the pro-inflammatory and immune responses in apolipoprotein E knockout mice

Chronic hyperbaric oxygen treatment elicits an anti-oxidant response and attenuates atherosclerosis in apo E  knockout mice

 

MUSCULOSKELETAL

Analgesic effect of hyperbaric oxygen therapy

Hyperbaric oxygen therapy for transient bone marrow oedema syndrome of the hip.

Effects of hyperbaric oxygen on gene expressions of procollagen, matrix metalloproteinase and tissue inhibitor of metalloproteinase in injured medial collateral ligament and anterior cruciate ligament

Effect of Hyperbaric Oxygen Therapy on Muscle Healing

The role and effectiveness of adjunctive hyperbaric oxygen therapy in the management of musculoskeletal disorders

Effect of different periods of hyperbaric oxygen on ischemia-reperfusion injury of rat skeletal muscle

Hyperbaric oxygen attenuates cell growth in skin fibroblasts cultured in a high-glucose medium

Effects of hyperbaric oxygen and platelet derived growth factor on medial collateral ligament fibroblasts

Hyperbaric oxygen and lymphoid system function: a review supporting possible intervention in tissue transplantation

Effects of hyperbaric oxygen treatment on tendon graft and tendon-bone integration in bone tunnel: biochemical and histological analysis in rabbits

Combined effect of hyberbaric oxygen and N-acetylcysteine on fibroblast proliferation

Effect of hyperbaric oxygen on the growth factor profile of fibroblasts

Hyperbaric oxygen induces basic fibroblast growth factor and hepatocyte growth factor expression, and enhances blood perfusion and muscle regeneration in mouse ischemic hind limbs

Hyperbaric oxygen improves contractile function of regenerating rat skeletal muscle after myotoxic injury

Effects of hyperbaric oxygen therapy on wound healing after tracheal resection and end-to-end anastomoses in rats: results of early observations

Effects of hyperbaric oxygen on energy production and xanthine oxidase levels in striated muscle tissue of healthy rats

Effects of hyperbaric oxygen on glucose, lactate, glycerol and anti-oxidant enzymes in the skeletal muscle of rats during ischaemia and reperfusion

Hyperbaric oxygenation and blood lactate clearance: study in sixty male naval cadets

Hyperbaric oxygen therapy facilitates surgery on complex open elbow injuries: Preliminary results

Hyperbaric oxygen therapy as a treatment for stage-I avascular necrosis of the femoral head

 

NEUROLOGIC

 

Improvement of clinical outcome and cerebral perfusion in a patient of atherosclerotic cerebral infarction after repetitive hyperbaric oxygen treatment–a case report and literature review

Effects of early hyperbaric oxygen therapy on clinical outcome in postoperative patients with intracranial aneurysm


Hyperbaric oxygen effect on MMP-9 after a vascular insult

Treatment of acute stroke with hyperbaric oxygen: time window for efficacy


Rationale of hyperbaric oxygenation in cerebral vascular insult


Mechanisms of hyperbaric oxygen and neuroprotection in stroke

Hyperbaric oxygen therapy and cerebral ischemia: neuroprotective mechanisms

Hyperbaric oxygen combined with intravenous edaravone for treatment of acute embolic stroke: a pilot clinical trial

Oxygen therapy improves energy metabolism in focal cerebral ischemia

Oxygen therapy reduces secondary hemorrhage after thrombolysis in thromboembolic cerebral ischemia

Oxygen therapy in acute ischemic stroke – experimental efficacy and molecular mechanisms

Hyperbaric oxygen for stroke treatment

Oxygen-sensitive outcomes and gene expression in acute ischemic stroke

Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease


Hyperbaric oxygen therapy in the treatment of post cardiac surgical strokes–a case series and review of the literature


Neuroprotective effects of hyperbaric oxygen treatment in experimental focal cerebral ischemia are associated with reduced brain leukocyte myeloperoxidase activity


Hyperbaric oxygen induces rapid protection against focal cerebral ischemia

Integrated brain restoration after ischemic stroke – medical management, risk factors, nutrients, and other ineterventions for managing inflammation and enhancing brain plasticity

Effect of large dose hyperbaric oxygenation therapy on prognosis and oxidative stress of acute permanent cerebral ischemic stroke in rats.

Hyperbaric oxygen therapy attenuates neuropathic hyperalgesia in rats and idiopathic trigeminal neuralgia in patients

Effects of hyperbaric oxygen therapy on facial nerve regeneration

Hyperbaric oxygen therapy and cerebral ischemia: neuroprotective mechanisms.

Hyperbaric oxygen in neurosurgery.

Oxygen therapy in acute ischemic stroke – experimental efficacy and molecular mechanisms.

 

PERIPHERAL NEUROPATHY

Effects of hyperbaric oxygen on peripheral nerves

The Efficacy Of Hyperbaric Oxygen Therapy For The Treatment Of Diabetic Autonomic Neuropathy

 

POST RADIATION

Early Hyperbaric Oxygen Therapy for Reducing Radiotherapy Side Effects: Early Results of a Randomized Trial in Oropharyngeal and Nasopharyngeal Cancer.

Improved Quality of Life with Hyperbaric Oxygen Therapy in Patients with Persistent Pelvic Radiation-induced Toxicity

Treatment of a radiation-induced rectal ulcer with hyperbaric oxygen therapy in a man with prostate cancer

Treatment of Radiation Induced Hemorrhagic Cystitis With Hyperbaric Oxygen

STEM CELLS

Hyperbaric oxygenation enhances transplanted cell graft and functional recovery in the infarct heart.

Non-hypoxic Stabilization of Hypoxia-Inducible Factor Alpha (HIF-alpha): Relevance in Neural Progenitor/Stem Cells.

Penn Study Finds Hyperbaric Oxygen Treatments Mobilize Stem Cells

Hyperbaric oxygen stimulates vasculogenic stem cell growth and differentiation in vivo

Hyperbaric oxygen induces placental growth factor expression in bone marrow-derived mesenchymal stem cells

Human Amniotic Fluid Mesenchymal Stem Cells in Combination with Hyperbaric Oxygen Augment Peripheral Nerve Regeneration

 

SURGICAL

Hyperbaric oxygen therapy as adjunctive treatment for postoperative cellulitis involving intrapelvic mesh.

Use of Hyperbaric Oxygen to Enhance Auricular Composite Graft Survival in the Rabbit Model

Facilitation of Recovery From Acute Blood Loss With Hyperbaric Oxygen

The effectiveness of hyperbaric oxygen treatment in tracheal reconstruction with auricular cartilage grafts (experimental study)

Preservation of organs from brain dead donors with hyperbaric oxygen

Hyperbaric oxygen preconditioning induces tolerance against spinal cord ischemia by upregulation of antioxidant enzymes in rabbits

Preconditioning with hyperbaric oxygen induces tolerance against oxidative injury via increased expression of heme oxygenase-1 in primary cultured spinal cord neurons

Hyperbaric oxygenation in peripheral nerve repair and regeneration (surgical repair in the acute peripheral nerve lesion)

 

GENITO-URINARY

Hyperbaric oxygen therapy for radiation cystitis in patients with prostate cancer: A long-term follow-up study

Hyperbaric oxygen therapy induces kidney protection in an ischemia/reperfusion model in rats.


Hyperbaric Oxygen Therapy for Radiation Cystitis in Patients with Prostate Cancer: A Long-Term Follow-Up Study

The effect of the hyperbaric oxygen and closed irrigation-suction therapy on the methicillin-resistant Staphylococcus aureus (MRSA) Osteomyelitis